Propofol suppresses synaptic responsiveness of somatosensory relay neurons to excitatory input by potentiating GABA<sub>A </sub>receptor chloride channels

<p>Abstract</p> <p>Propofol is a widely used intravenous general anesthetic. Propofol-induced unconsciousness in humans is associated with inhibition of thalamic activity evoked by somatosensory stimuli. However, the cellular mechanisms underlying the effects of propofol in thalami...

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Bibliographic Details
Main Authors: Goldstein Peter A, Ying Shui-Wang
Format: Article
Language:English
Published: SAGE Publishing 2005-01-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/1/1/2