Increasing the physical size and nucleation status of human pluripotent stem cell-derived ventricular cardiomyocytes by cell fusion

Increasing the physical size and nucleation status of human pluripotent stem cell-derived ventricular cardiomyocytes by cell fusion

Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) provide an unlimited source of donor cells for potential cardiac regenerative therapies. However, hPSC-CMs are immature. For instance, hPSC-CMs are only 1/10 of the physical size of their adult counterparts; the majority are mono- rather...

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Bibliographic Details
Main Authors:	Chi-Wing Kong, Shuxun Chen, Lin Geng, Angie Man-Yee Shum, Dong Sun, Ronald A Li
Format:	Article
Language:	English
Published:	Elsevier 2017-03-01
Series:	Stem Cell Research
Subjects:	Human pluripotent stem cell-derived ventricular cardiomyocytes (hPSC-VCMs) Cell fusion Hypertrophy Multi-nucleation Electrophysiological maturation
Online Access:	http://www.sciencedirect.com/science/article/pii/S187350611730003X

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