An approach for exploring interaction between two proteins in vivo

We describe a strategy for exploring the function of protein-protein interactions in striated muscle in vivo. We describe our experience using this strategy to study the interaction of UNC-112 (kindlin) with PAT-4 (integrin linked kinase). Random mutagenesis is used to generate a collection of mutan...

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Bibliographic Details
Main Authors: Hiroshi eQadota, Guy M Benian
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00162/full