DMF-MALDI: droplet based microfluidic combined to MALDI-TOF for focused peptide detection

Abstract We present an automated droplet microfluidic system (DMF) to generate monitored nanoliter aqueous droplets in oil and their deposition on a commercial stainless steel plate for MALDI-TOF analysis of peptides or protein digests. We demonstrate that DMF-MALDI combination focuses the analyte o...

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Bibliographic Details
Main Authors: Kiarach Mesbah, Robert Thai, Sarah Bregant, Florent Malloggi
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06660-8