Characterizing genetic interactions in human disease association studies using statistical epistasis networks

<p>Abstract</p> <p>Background</p> <p>Epistasis is recognized ubiquitous in the genetic architecture of complex traits such as disease susceptibility. Experimental studies in model organisms have revealed extensive evidence of biological interactions among genes. Meanwhi...

Full description

Bibliographic Details
Main Authors: Andrew Angeline S, Kiralis Jeff W, Sinnott-Armstrong Nicholas A, Hu Ting, Karagas Margaret R, Moore Jason H
Format: Article
Language:English
Published: BMC 2011-09-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/364