Identification of a Candidate Gene Set Signature for the Risk of Progression in IgM MGUS to Smoldering/Symptomatic <i>Waldenström</i> Macroglobulinemia (WM) by a Comparative Transcriptome Analysis of B Cells and Plasma Cells

Identification of a Candidate Gene Set Signature for the Risk of Progression in IgM MGUS to Smoldering/Symptomatic <i>Waldenström</i> Macroglobulinemia (WM) by a Comparative Transcriptome Analysis of B Cells and Plasma Cells

<i>Waldenström</i> Macroglobulinemia (WM) is a B-cell lymphoma characterized by the precursor condition IgM monoclonal gammopathies of undetermined significance (IgM MGUS). We performed a gene expression profiling study to compare the transcriptome signatures of bone marrow (BM) B-cells...

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Bibliographic Details
Main Authors: Alessandra Trojani, Barbara Di Camillo, Luca Emanuele Bossi, Livia Leuzzi, Antonino Greco, Alessandra Tedeschi, Anna Maria Frustaci, Marina Deodato, Giulia Zamprogna, Alessandro Beghini, Roberto Cairoli
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
<i>Waldenström</i> Macroglobulinemia
IgM monoclonal gammopathies of undetermined significance
gene expression profiling
DEGs (differentially expressed genes)
KEGG signaling pathways
Online Access:https://www.mdpi.com/2072-6694/13/8/1837

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