Restoration of the methylation status of hypermethylated gene promoters by microRNA-29b in human breast cancer: A novel epigenetic therapeutic approach
It is well established that transcriptional silencing of critical tumor-suppressor genes by DNA methylation is a fundamental component in the initiation of breast cancer. However, the involvement of microRNAs (miRNAs) in restoring abnormal DNA methylation patterns in breast cancer is not well unders...
Main Authors: | Athena Starlard-Davenport, Kristi Kutanzi, Volodymyr Tryndyak, Beverly Word, Beverly Lyn-Cook |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2013-01-01
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Series: | Journal of Carcinogenesis |
Subjects: | |
Online Access: | http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2013;volume=12;issue=1;spage=15;epage=15;aulast=Starlard-Davenport |
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