Restoration of the methylation status of hypermethylated gene promoters by microRNA-29b in human breast cancer: A novel epigenetic therapeutic approach

It is well established that transcriptional silencing of critical tumor-suppressor genes by DNA methylation is a fundamental component in the initiation of breast cancer. However, the involvement of microRNAs (miRNAs) in restoring abnormal DNA methylation patterns in breast cancer is not well unders...

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Bibliographic Details
Main Authors: Athena Starlard-Davenport, Kristi Kutanzi, Volodymyr Tryndyak, Beverly Word, Beverly Lyn-Cook
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Journal of Carcinogenesis
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Online Access:http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2013;volume=12;issue=1;spage=15;epage=15;aulast=Starlard-Davenport

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