PTEN/PTENP1: ‘Regulating the regulator of RTK-dependent PI3K/Akt signalling’, new targets for cancer therapy

PTEN/PTENP1: ‘Regulating the regulator of RTK-dependent PI3K/Akt signalling’, new targets for cancer therapy

Abstract Regulation of the PI-3 kinase (PI3K)/Akt signalling pathway is essential for maintaining the integrity of fundamental cellular processes, cell growth, survival, death and metabolism, and dysregulation of this pathway is implicated in the development and progression of cancers. Receptor tyro...

Full description

Bibliographic Details
Main Authors: Nahal Haddadi, Yiguang Lin, Glena Travis, Ann M. Simpson, Najah T. Nassif, Eileen M. McGowan
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Molecular Cancer
Subjects:
Phosphatase and tensin homologue (PTEN)
PTENP1
Pseudogene
Tyrosine kinase
PI-3 kinase (PI3K)
Cancer
Online Access:http://link.springer.com/article/10.1186/s12943-018-0803-3

Internet

http://link.springer.com/article/10.1186/s12943-018-0803-3

Similar Items