Inference of Candidate Germline Mutator Loci in Humans from Genome-Wide Haplotype Data.

The rate of germline mutation varies widely between species but little is known about the extent of variation in the germline mutation rate between individuals of the same species. Here we demonstrate that an allele that increases the rate of germline mutation can result in a distinctive signature i...

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Bibliographic Details
Main Authors: Cathal Seoighe, Aylwyn Scally
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5283766?pdf=render