Neurotrophic Factor BDNF, Physiological Functions and Therapeutic Potential in Depression, Neurodegeneration and Brain Cancer

Neurotrophic Factor BDNF, Physiological Functions and Therapeutic Potential in Depression, Neurodegeneration and Brain Cancer

Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin receptor kinase B (TrkB) and the low affinity p75 neurotrophin receptor (p75NTR). BDNF plays an important role in proper growth, d...

Full description

Bibliographic Details
Main Authors: Luca Colucci-D’Amato, Luisa Speranza, Floriana Volpicelli
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
BDNF
miRNAs
neurogenesis
synaptic plasticity
depression
neurodegeneration
Online Access:https://www.mdpi.com/1422-0067/21/20/7777

Similar Items

Similar Items