A Quarter Century of Liver Transplantation: Learning from Livers
Liver transplantation has emerged as a powerful tool to increase the understanding of physiological and pathophysiological processes in the liver. Transplantation for metabolic diseases with resolution of the disease process has been the ultimate proof of the hepatic source of the defect. Recurrence...
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| Format: | Article |
| Language: | English |
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Hindawi Limited
1989-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1989/695761 |
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doaj-e65a29b1256b49d98fccca397fae8ba52020-11-24T23:30:06ZengHindawi LimitedCanadian Journal of Gastroenterology0835-79001989-01-013416216410.1155/1989/695761A Quarter Century of Liver Transplantation: Learning from LiversPaul C. Adams0University Hospital, University of Western Ontario, London, Ontario, CanadaLiver transplantation has emerged as a powerful tool to increase the understanding of physiological and pathophysiological processes in the liver. Transplantation for metabolic diseases with resolution of the disease process has been the ultimate proof of the hepatic source of the defect. Recurrence of the primary disease in the liver following transplantation has furthered understanding of the pathogenesis of hepatitis and the cell biology of hepatobiliary tumours. The role of genetics and immune factors in the pathogenesis of alcoholic I iver disease may be clarified with the increasing numbers of patients transplanted for alcoholic cirrhosis. Normal gallbladder motility in the denervated transplanted liver questions the role of neuronal influences on gallbladder function. Finally, experimental liver transplantation in animals has been used as a tool to study metabolic problems.http://dx.doi.org/10.1155/1989/695761 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Paul C. Adams |
| spellingShingle |
Paul C. Adams A Quarter Century of Liver Transplantation: Learning from Livers Canadian Journal of Gastroenterology |
| author_facet |
Paul C. Adams |
| author_sort |
Paul C. Adams |
| title |
A Quarter Century of Liver Transplantation: Learning from Livers |
| title_short |
A Quarter Century of Liver Transplantation: Learning from Livers |
| title_full |
A Quarter Century of Liver Transplantation: Learning from Livers |
| title_fullStr |
A Quarter Century of Liver Transplantation: Learning from Livers |
| title_full_unstemmed |
A Quarter Century of Liver Transplantation: Learning from Livers |
| title_sort |
quarter century of liver transplantation: learning from livers |
| publisher |
Hindawi Limited |
| series |
Canadian Journal of Gastroenterology |
| issn |
0835-7900 |
| publishDate |
1989-01-01 |
| description |
Liver transplantation has emerged as a powerful tool to increase
the understanding of physiological and pathophysiological processes in the liver.
Transplantation for metabolic diseases with resolution of the disease process has
been the ultimate proof of the hepatic source of the defect. Recurrence of the
primary disease in the liver following transplantation has furthered understanding
of the pathogenesis of hepatitis and the cell biology of hepatobiliary
tumours. The role of genetics and immune factors in the pathogenesis of alcoholic
I iver disease may be clarified with the increasing numbers of patients transplanted
for alcoholic cirrhosis. Normal gallbladder motility in the denervated
transplanted liver questions the role of neuronal influences on gallbladder
function. Finally, experimental liver transplantation in animals has been used as
a tool to study metabolic problems. |
| url |
http://dx.doi.org/10.1155/1989/695761 |
| work_keys_str_mv |
AT paulcadams aquartercenturyoflivertransplantationlearningfromlivers AT paulcadams quartercenturyoflivertransplantationlearningfromlivers |
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