First trimester serum PAPP-A levels and the prediction of small-for-gestational age infants

First trimester serum PAPP-A levels and the prediction of small-for-gestational age infants

Objectives: The aim of this study was to detect thepredictive value of PAPP-A in small-for-gestational age(SGA) infants.Materials and methods: We retrospectively searchedthe patient charts of our hospital for first trimester Downsyndrome screening test results. PAPP-A levels less than5th percentile...

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Bibliographic Details
Main Authors: Nilgün Güdücü, Gökçenur Gönenç, Herman İşçi, Alin Başgül Yiğiter, İlkkan Dünder
Format: Article
Language:English
Published: Modestum Publishing LTD 2012-06-01
Series:Journal of Clinical and Experimental Investigations
Subjects:
Small for gestational age
PAPP-A
pregnancy
Online Access:http://www.jceionline.org/upload/sayi/12/JCEI-00307.pdf
Description
Summary:Objectives: The aim of this study was to detect thepredictive value of PAPP-A in small-for-gestational age(SGA) infants.Materials and methods: We retrospectively searchedthe patient charts of our hospital for first trimester Downsyndrome screening test results. PAPP-A levels less than5th percentile were considered as predictive of SGA infants.Results: Low PAPP-A levels were associated with SGAinfants, sensitivity was 3,5%, specificity 90%, positivepredictive value 1,6% and negative predictive value 95%.Conclusions: The low positive predictive value of PAPPAprevents it from being used as a screening test for thedetection of SGA infants. J Clin Exp Invest 2012; 3(2):185-188
ISSN:1309-8578
1309-6621

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