TOPical Imiquimod treatment of residual or recurrent cervical intraepithelial neoplasia (TOPIC-2 trial): a study protocol for a randomized controlled trial

Abstract Background Cervical dysplasia (cervical intraepithelial neoplasia (CIN)) is caused by Human Papillomavirus (HPV) and is most common in women of reproductive age. Current treatment of moderate to severe CIN is surgical. This procedure has potential complications, such as haemorrhage, infecti...

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Bibliographic Details
Main Authors: A. J. M. van de Sande, M. M. Koeneman, C. G. Gerestein, A. J. Kruse, F. J. van Kemenade, H. J. van Beekhuizen
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-018-4510-7