Caffeic Acid, Quercetin and 5-Fluorocytidine-Functionalized Au-Fe<sub>3</sub>O<sub>4</sub> Nanoheterodimers for X-ray-Triggered Drug Delivery in Breast Tumor Spheroids

Caffeic Acid, Quercetin and 5-Fluorocytidine-Functionalized Au-Fe<sub>3</sub>O<sub>4</sub> Nanoheterodimers for X-ray-Triggered Drug Delivery in Breast Tumor Spheroids

Au-Fe<sub>3</sub>O<sub>4</sub> nanoheterodimers (NHD) were functionalized with the natural and synthetic anticancer drugs caffeic acid (CA), quercetin (Q) and 5-fluorocytidine (5FC). Their X-radiation dose-enhancing potential and chemotherapeutic efficacy for bimodal cancer t...

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Bibliographic Details
Main Authors: Stefanie Klein, Luitpold V. R. Distel, Winfried Neuhuber, Carola Kryschi
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Nanomaterials
Subjects:
multicellular tumor spheroid
Au-Fe<sub>3</sub>O<sub>4</sub> nanoheterodimers
radiotherapy
chemotherapy
X-ray-triggered drug delivery
Online Access:https://www.mdpi.com/2079-4991/11/5/1167

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https://www.mdpi.com/2079-4991/11/5/1167

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