Peutz-Jeghers syndrome and duodeno-jejunal adenocarcinoma: therapeutic implications Síndrome de Peutz-Jeghers y adenocarcinoma duodenal-yeyunal: implicaciones terapéuticas

Peutz-Jeghers syndrome and duodeno-jejunal adenocarcinoma: therapeutic implications Síndrome de Peutz-Jeghers y adenocarcinoma duodenal-yeyunal: implicaciones terapéuticas

The Peutz-Jeghers syndrome (PJS) is an autosomal dominant hamartomatous poliposis describred in 1921. Hemminki in 1997 described the presence of LKB-1 mutation tumor-suppressor gen. The patients with PJS develop a higher cumulative incidence of gastrointestinal, pancreas and extraintestinal tumors,...

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Bibliographic Details
Main Authors: J. A. Cienfuegos, J. Baixauli, G. Zozaya, A. Bueno, J. Arredondo, F. M. Regueira, R. Angós, J. L. Hernández-Lizoáin, M. A. Idoate
Format: Article
Language:English
Published: Aran Ediciones 2009-12-01
Series:Revista Espanola de Enfermedades Digestivas
Subjects:
Peutz-Jeghers syndrome
Hamartomatous
Carcinogenesis
Intestinal polyposis
Hereditary cancer
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082009001200009

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http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082009001200009

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