Theoretical analysis of inducer and operator binding for cyclic-AMP receptor protein mutants.

Allosteric transcription factors undergo binding events at inducer binding sites as well as at distinct DNA binding domains, and it is difficult to disentangle the structural and functional consequences of these two classes of interactions. We compare the ability of two statistical mechanical models...

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Bibliographic Details
Main Authors: Tal Einav, Julia Duque, Rob Phillips
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6157895?pdf=render