Predisposition to Apoptosis in Hepatocellular Carcinoma: From Mechanistic Insights to Therapeutic Strategies

Predisposition to Apoptosis in Hepatocellular Carcinoma: From Mechanistic Insights to Therapeutic Strategies

Hepatocellular carcinoma (HCC) ranks among the most rapidly evolving cancers in the Western world. The majority of HCCs develop on the basis of a chronic inflammatory liver damage that predisposes liver cancer development and leads to deregulation of multiple cellular signaling pathways. The resulti...

Full description

Bibliographic Details
Main Authors: Jens U. Marquardt, Frank Edlich
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma
cell death
inflammation
BCL-2 family
BH3
primed to death
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01421/full

Similar Items

Similar Items