The Determination of Melanoma Stage at Diagnosis

The rising proportion of melanomas diagnosed at an early pathologic stage is commonly ascribed to better public education. However in the US SEER program of cancer registration it has been found that the rates for in situ melanomas are closely related by a log linear relationship to the incidence of...

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Main Author: John A. H. Lee
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Dermatology Research and Practice
Online Access:http://dx.doi.org/10.1155/2010/839829
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spelling doaj-e62e88cd3cce43dab82699ace403962d2020-11-24T22:26:00ZengHindawi LimitedDermatology Research and Practice1687-61051687-61132010-01-01201010.1155/2010/839829839829The Determination of Melanoma Stage at DiagnosisJohn A. H. Lee0Fred Hutchinson Cancer Research Center, M4-B874, 1100 Fairview Avenue N, Seattle, WA 98109, USAThe rising proportion of melanomas diagnosed at an early pathologic stage is commonly ascribed to better public education. However in the US SEER program of cancer registration it has been found that the rates for in situ melanomas are closely related by a log linear relationship to the incidence of invasive melanomas and that this relationship is unrelated to calendar year or gender or patient age. This relationship is sufficiently strong to leave little room for other factors. The relationship may be different in populations with different melanoma rates and responses to them. It is suggested that the results are due to variations within populations of individual response to melanoma cell proliferation.http://dx.doi.org/10.1155/2010/839829
collection DOAJ
language English
format Article
sources DOAJ
author John A. H. Lee
spellingShingle John A. H. Lee
The Determination of Melanoma Stage at Diagnosis
Dermatology Research and Practice
author_facet John A. H. Lee
author_sort John A. H. Lee
title The Determination of Melanoma Stage at Diagnosis
title_short The Determination of Melanoma Stage at Diagnosis
title_full The Determination of Melanoma Stage at Diagnosis
title_fullStr The Determination of Melanoma Stage at Diagnosis
title_full_unstemmed The Determination of Melanoma Stage at Diagnosis
title_sort determination of melanoma stage at diagnosis
publisher Hindawi Limited
series Dermatology Research and Practice
issn 1687-6105
1687-6113
publishDate 2010-01-01
description The rising proportion of melanomas diagnosed at an early pathologic stage is commonly ascribed to better public education. However in the US SEER program of cancer registration it has been found that the rates for in situ melanomas are closely related by a log linear relationship to the incidence of invasive melanomas and that this relationship is unrelated to calendar year or gender or patient age. This relationship is sufficiently strong to leave little room for other factors. The relationship may be different in populations with different melanoma rates and responses to them. It is suggested that the results are due to variations within populations of individual response to melanoma cell proliferation.
url http://dx.doi.org/10.1155/2010/839829
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