Metabotropic Glutamate Receptor Subtype 5 in Alcohol-Induced Negative Affect

Metabotropic Glutamate Receptor Subtype 5 in Alcohol-Induced Negative Affect

Allosteric modulators of metabotropic glutamate 5 receptors (mGlu<sub>5</sub> receptors) have been identified as a promising treatment to independently alleviate both negative affective states and ethanol-seeking and intake. However, these conditions are often comorbid and might precipit...

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Bibliographic Details
Main Authors: Chelsea R. Kasten, Eleanor B. Holmgren, Tiffany A. Wills
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Brain Sciences
Subjects:
alcohol
negative affect
despair
anxiety
mGlu5
sex differences
ethanol dependence
Online Access:https://www.mdpi.com/2076-3425/9/8/183

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