Stereospermum tetragonam as an antidiabetic agent by activating PPARγ and GLUT4
Present study evaluates the anti-diabetic activity of S. tetragonam LC-MS/MS experiments showed the presence of two novel molecules C1 and C2, which were further taken for in silico study against PPARγ. Cell culture studies with A431 cells in the presence of crude aqueous extract showed the elevated...
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Bangladesh Pharmacological Society
2014-06-01
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| Series: | Bangladesh Journal of Pharmacology |
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| Online Access: | https://www.banglajol.info/index.php/BJP/article/view/18488 |
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doaj-e627b28a63b748c1adc5ecd9ca191d962020-11-25T01:46:54ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-00882014-06-019210.3329/bjp.v9i2.18488Stereospermum tetragonam as an antidiabetic agent by activating PPARγ and GLUT4Bino Kingsley0K. P. Arun1Stalin Selvaraj2Brindha Pemiah3School of Chemical and Biotechnology, SASTRA University, Thanjavur 613 401, Tamil NaduSchool of Chemical and Biotechnology, SASTRA University, Thanjavur 613 401School of chemical & Biotechnology, SASTRA University, Thanjavur 613 401.TamilNaduSchool of chemical & Biotechnology, SASTRA University, Thanjavur 613 401Present study evaluates the anti-diabetic activity of S. tetragonam LC-MS/MS experiments showed the presence of two novel molecules C1 and C2, which were further taken for in silico study against PPARγ. Cell culture studies with A431 cells in the presence of crude aqueous extract showed the elevated level of PPARγ and GLUT4 and also confirmed using in silico studies. Thus, the present study proves the mecode of action of S. tetragonam as an antidiabetic drug. https://www.banglajol.info/index.php/BJP/article/view/18488DiabetesGLUT-4in silicoPPARγStereospermum tetragonam |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Bino Kingsley K. P. Arun Stalin Selvaraj Brindha Pemiah |
| spellingShingle |
Bino Kingsley K. P. Arun Stalin Selvaraj Brindha Pemiah Stereospermum tetragonam as an antidiabetic agent by activating PPARγ and GLUT4 Bangladesh Journal of Pharmacology Diabetes GLUT-4 in silico PPARγ Stereospermum tetragonam |
| author_facet |
Bino Kingsley K. P. Arun Stalin Selvaraj Brindha Pemiah |
| author_sort |
Bino Kingsley |
| title |
Stereospermum tetragonam as an antidiabetic agent by activating PPARγ and GLUT4 |
| title_short |
Stereospermum tetragonam as an antidiabetic agent by activating PPARγ and GLUT4 |
| title_full |
Stereospermum tetragonam as an antidiabetic agent by activating PPARγ and GLUT4 |
| title_fullStr |
Stereospermum tetragonam as an antidiabetic agent by activating PPARγ and GLUT4 |
| title_full_unstemmed |
Stereospermum tetragonam as an antidiabetic agent by activating PPARγ and GLUT4 |
| title_sort |
stereospermum tetragonam as an antidiabetic agent by activating pparγ and glut4 |
| publisher |
Bangladesh Pharmacological Society |
| series |
Bangladesh Journal of Pharmacology |
| issn |
1991-0088 |
| publishDate |
2014-06-01 |
| description |
Present study evaluates the anti-diabetic activity of S. tetragonam LC-MS/MS experiments showed the presence of two novel molecules C1 and C2, which were further taken for in silico study against PPARγ. Cell culture studies with A431 cells in the presence of crude aqueous extract showed the elevated level of PPARγ and GLUT4 and also confirmed using in silico studies. Thus, the present study proves the mecode of action of S. tetragonam as an antidiabetic drug.
|
| topic |
Diabetes GLUT-4 in silico PPARγ Stereospermum tetragonam |
| url |
https://www.banglajol.info/index.php/BJP/article/view/18488 |
| work_keys_str_mv |
AT binokingsley stereospermumtetragonamasanantidiabeticagentbyactivatingppargandglut4 AT kparun stereospermumtetragonamasanantidiabeticagentbyactivatingppargandglut4 AT stalinselvaraj stereospermumtetragonamasanantidiabeticagentbyactivatingppargandglut4 AT brindhapemiah stereospermumtetragonamasanantidiabeticagentbyactivatingppargandglut4 |
| _version_ |
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