Dance with the Devil: Stress Granules and Signaling in Antiviral Responses

Cells have evolved highly specialized sentinels that detect viral infection and elicit an antiviral response. Among these, the stress-sensing protein kinase R, which is activated by double-stranded RNA, mediates suppression of the host translation machinery as a strategy to limit viral replication....

Full description

Bibliographic Details
Main Authors: Nina Eiermann, Katharina Haneke, Zhaozhi Sun, Georg Stoecklin, Alessia Ruggieri
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Viruses
Subjects:
PKR
Online Access:https://www.mdpi.com/1999-4915/12/9/984