Management of residual mass in nonseminomatous germ cell tumors following chemotherapy

Advanced stage nonseminomatous testis cancer is commonly treated with chemotherapy and surgical resection. Patients with retroperitoneal residual masses >1cm following induction chemotherapy with normalized tumor markers should undergo a post-chemotherapy retroperitoneal lymph node dissection. Po...

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Main Authors: Siamak Daneshmand, Hooman Djaladat, Craig Nichols
Format: Article
Language:English
Published: SAGE Publishing 2011-08-01
Series:Therapeutic Advances in Urology
Online Access:https://doi.org/10.1177/1756287211418721
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spelling doaj-e6110c4e5b6d4651816776962abc682f2020-11-25T03:24:02ZengSAGE PublishingTherapeutic Advances in Urology1756-28721756-28802011-08-01310.1177/1756287211418721Management of residual mass in nonseminomatous germ cell tumors following chemotherapySiamak DaneshmandHooman DjaladatCraig NicholsAdvanced stage nonseminomatous testis cancer is commonly treated with chemotherapy and surgical resection. Patients with retroperitoneal residual masses >1cm following induction chemotherapy with normalized tumor markers should undergo a post-chemotherapy retroperitoneal lymph node dissection. Post chemotherapy retroperitoneal residual mass less than 1 cm with normal markers may be considered as complete response, although the possibility of residual teratoma and viable germ cell tumor are not definitively ruled out. Excellent long term disease free survival following surveillance may justify this option as the treatment of choice in this cohort of patients.https://doi.org/10.1177/1756287211418721
collection DOAJ
language English
format Article
sources DOAJ
author Siamak Daneshmand
Hooman Djaladat
Craig Nichols
spellingShingle Siamak Daneshmand
Hooman Djaladat
Craig Nichols
Management of residual mass in nonseminomatous germ cell tumors following chemotherapy
Therapeutic Advances in Urology
author_facet Siamak Daneshmand
Hooman Djaladat
Craig Nichols
author_sort Siamak Daneshmand
title Management of residual mass in nonseminomatous germ cell tumors following chemotherapy
title_short Management of residual mass in nonseminomatous germ cell tumors following chemotherapy
title_full Management of residual mass in nonseminomatous germ cell tumors following chemotherapy
title_fullStr Management of residual mass in nonseminomatous germ cell tumors following chemotherapy
title_full_unstemmed Management of residual mass in nonseminomatous germ cell tumors following chemotherapy
title_sort management of residual mass in nonseminomatous germ cell tumors following chemotherapy
publisher SAGE Publishing
series Therapeutic Advances in Urology
issn 1756-2872
1756-2880
publishDate 2011-08-01
description Advanced stage nonseminomatous testis cancer is commonly treated with chemotherapy and surgical resection. Patients with retroperitoneal residual masses >1cm following induction chemotherapy with normalized tumor markers should undergo a post-chemotherapy retroperitoneal lymph node dissection. Post chemotherapy retroperitoneal residual mass less than 1 cm with normal markers may be considered as complete response, although the possibility of residual teratoma and viable germ cell tumor are not definitively ruled out. Excellent long term disease free survival following surveillance may justify this option as the treatment of choice in this cohort of patients.
url https://doi.org/10.1177/1756287211418721
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AT craignichols managementofresidualmassinnonseminomatousgermcelltumorsfollowingchemotherapy
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