Dysregulation of ribosome biogenesis and translational capacity is associated with tumor progression of human breast cancer cells.

Dysregulation of ribosome biogenesis and translational capacity is associated with tumor progression of human breast cancer cells.

Protein synthesis is a fundamental cell process and ribosomes - particularly through the ribosomal RNA that display ribozyme activity--are the main effectors of this process. Ribosome biogenesis is a very complex process involving transcriptional aswell as many post-transcriptional steps to produce...

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Bibliographic Details
Main Authors: Stéphane Belin, Anne Beghin, Eduardo Solano-Gonzàlez, Laurent Bezin, Stéphanie Brunet-Manquat, Julien Textoris, Anne-Catherine Prats, Hichem C Mertani, Charles Dumontet, Jean-Jacques Diaz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19779612/pdf/?tool=EBI

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