Genomic Insertion of a Heterologous Acetyltransferase Generates a New Lipopolysaccharide Antigenic Structure in Brucella abortus and Brucella melitensis

Genomic Insertion of a Heterologous Acetyltransferase Generates a New Lipopolysaccharide Antigenic Structure in Brucella abortus and Brucella melitensis

Brucellosis is a bacterial zoonosis of worldwide distribution caused by bacteria of the genus Brucella. In Brucella abortus and Brucella melitensis, the major species infecting domestic ruminants, the smooth lipopolysaccharide (S-LPS) is a virulence factor. This S-LPS carries a N-formyl-perosamine h...

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Bibliographic Details
Main Authors:	Estrella Martínez-Gómez, Jonas Ståhle, Yolanda Gil-Ramírez, Amaia Zúñiga-Ripa, Mona Zaccheus, Ignacio Moriyón, Maite Iriarte, Göran Widmalm, Raquel Conde-Álvarez
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-05-01
Series:	Frontiers in Microbiology
Subjects:	lipopolysaccharide (LPS) bacterial pathogenesis bacteria vaccine development virulence factor antigen
Online Access:	https://www.frontiersin.org/article/10.3389/fmicb.2018.01092/full

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