Non-covalent binding analysis of sulfamethoxazole to human serum albumin: Fluorescence spectroscopy, UVâvis, FT-IR, voltammetric and molecular modeling

This study was designed to examine the interaction of sulfamethoxazole (SMZ) with human serum albumin(HSA). Spectroscopic analysis of the emission quenching at different temperatures revealed that the quenching mechanism of human serum albumin by SMZ was static mechanism. The binding constant values...

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Bibliographic Details
Main Authors: Praveen N. Naik, Sharanappa T. Nandibewoor, Shivamurthi A. Chimatadar
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177915000143

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