The interhemispheric CA1 circuit governs rapid generalisation but not fear memory

Previous work has documented a slow form of memory generalization although a rapid one is demanded. Here the authors elucidate the role of the interhemispheric CA1-CA1 projection in a form of rapid generalization of contextual fear memory via gradual potentiation of these synapses over 24 h.

Bibliographic Details
Main Authors: Heng Zhou, Gui-Jing Xiong, Liang Jing, Ning-Ning Song, De-Lin Pu, Xun Tang, Xiao-Bing He, Fu-Qiang Xu, Jing-Fei Huang, Ling-Jiang Li, Gal Richter-Levin, Rong-Rong Mao, Qi-Xin Zhou, Yu-Qiang Ding, Lin Xu
Format: Article
Language:English
Published: Nature Publishing Group 2017-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02315-4
Description
Summary:Previous work has documented a slow form of memory generalization although a rapid one is demanded. Here the authors elucidate the role of the interhemispheric CA1-CA1 projection in a form of rapid generalization of contextual fear memory via gradual potentiation of these synapses over 24 h.
ISSN:2041-1723