Structure of an Acinetobacter Broad-Range Prophage Endolysin Reveals a C-Terminal α-Helix with the Proposed Role in Activity against Live Bacterial Cells

Structure of an Acinetobacter Broad-Range Prophage Endolysin Reveals a C-Terminal α-Helix with the Proposed Role in Activity against Live Bacterial Cells

Proteins that include enzymatic domain degrading the bacterial cell wall and a domain providing transport through the bacterial outer membrane are considered as prospective compounds to combat pathogenic Gram-negative bacteria. This paper presents an isolation and study of an enzyme of this class na...

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Bibliographic Details
Main Authors: Nina N. Sykilinda, Alena Y. Nikolaeva, Mikhail M. Shneider, Dmitry V. Mishkin, Artem A. Patutin, Vladimir O. Popov, Konstantin M. Boyko, Natalia L. Klyachko, Konstantin A. Miroshnikov
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Viruses
Subjects:
endolysin
peptidoglycan hydrolase
Acinetobacter
prophage
structure
α-helix
Online Access:http://www.mdpi.com/1999-4915/10/6/309

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