Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules
In this work, new trans-diamide derivatives were synthesized with the reaction between fumaryl chloride and substituted anilines. After the successful synthesis of trans-amides, the antioxidant activity of all synthesized molecules was investigated via the DPPH method and calculated IC50 values. Al...
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doaj-e5d78d0c4f75446f94091147e51b0bd22020-11-25T02:56:54ZengTurkish Chemical SocietyJournal of the Turkish Chemical Society, Section A: Chemistry2149-01202020-02-0171143150https://doi.org/10.18596/jotcsa.627805Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized moleculesÖzgür YILMAZ0https://orcid.org/0000-0001-9278-1091Mersin University In this work, new trans-diamide derivatives were synthesized with the reaction between fumaryl chloride and substituted anilines. After the successful synthesis of trans-amides, the antioxidant activity of all synthesized molecules was investigated via the DPPH method and calculated IC50 values. All trans-amides were characterized by 1H-NMR, 13C-NMR, 19F-NMR, GC-MS and FTIR spectroscopic techniques.https://dergipark.org.tr/en/pub/jotcsa/issue/49279/627805amidesdpph methodantioxidant activity |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Özgür YILMAZ |
spellingShingle |
Özgür YILMAZ Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules Journal of the Turkish Chemical Society, Section A: Chemistry amides dpph method antioxidant activity |
author_facet |
Özgür YILMAZ |
author_sort |
Özgür YILMAZ |
title |
Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules |
title_short |
Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules |
title_full |
Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules |
title_fullStr |
Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules |
title_full_unstemmed |
Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules |
title_sort |
synthesis of trans-diamide derivatives from fumaryl chloride and determination of dpph scavenging activity of synthesized molecules |
publisher |
Turkish Chemical Society |
series |
Journal of the Turkish Chemical Society, Section A: Chemistry |
issn |
2149-0120 |
publishDate |
2020-02-01 |
description |
In this work, new trans-diamide derivatives were synthesized with the reaction between fumaryl chloride and substituted anilines. After the successful synthesis of trans-amides, the antioxidant activity of all synthesized molecules was investigated via the DPPH method and calculated IC50 values. All trans-amides were characterized by 1H-NMR, 13C-NMR, 19F-NMR, GC-MS and FTIR spectroscopic techniques. |
topic |
amides dpph method antioxidant activity |
url |
https://dergipark.org.tr/en/pub/jotcsa/issue/49279/627805 |
work_keys_str_mv |
AT ozguryilmaz synthesisoftransdiamidederivativesfromfumarylchlorideanddeterminationofdpphscavengingactivityofsynthesizedmolecules |
_version_ |
1724711751622066176 |