Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules

In this work, new trans-diamide derivatives were synthesized with the reaction between fumaryl chloride and substituted anilines. After the successful synthesis of trans-amides, the antioxidant activity of all synthesized molecules was investigated via the DPPH method and calculated IC50 values. Al...

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Main Author: Özgür YILMAZ
Format: Article
Language:English
Published: Turkish Chemical Society 2020-02-01
Series:Journal of the Turkish Chemical Society, Section A: Chemistry
Subjects:
Online Access:https://dergipark.org.tr/en/pub/jotcsa/issue/49279/627805
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spelling doaj-e5d78d0c4f75446f94091147e51b0bd22020-11-25T02:56:54ZengTurkish Chemical SocietyJournal of the Turkish Chemical Society, Section A: Chemistry2149-01202020-02-0171143150https://doi.org/10.18596/jotcsa.627805Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized moleculesÖzgür YILMAZ0https://orcid.org/0000-0001-9278-1091Mersin University In this work, new trans-diamide derivatives were synthesized with the reaction between fumaryl chloride and substituted anilines. After the successful synthesis of trans-amides, the antioxidant activity of all synthesized molecules was investigated via the DPPH method and calculated IC50 values. All trans-amides were characterized by 1H-NMR, 13C-NMR, 19F-NMR, GC-MS and FTIR spectroscopic techniques.https://dergipark.org.tr/en/pub/jotcsa/issue/49279/627805amidesdpph methodantioxidant activity
collection DOAJ
language English
format Article
sources DOAJ
author Özgür YILMAZ
spellingShingle Özgür YILMAZ
Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules
Journal of the Turkish Chemical Society, Section A: Chemistry
amides
dpph method
antioxidant activity
author_facet Özgür YILMAZ
author_sort Özgür YILMAZ
title Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules
title_short Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules
title_full Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules
title_fullStr Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules
title_full_unstemmed Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules
title_sort synthesis of trans-diamide derivatives from fumaryl chloride and determination of dpph scavenging activity of synthesized molecules
publisher Turkish Chemical Society
series Journal of the Turkish Chemical Society, Section A: Chemistry
issn 2149-0120
publishDate 2020-02-01
description In this work, new trans-diamide derivatives were synthesized with the reaction between fumaryl chloride and substituted anilines. After the successful synthesis of trans-amides, the antioxidant activity of all synthesized molecules was investigated via the DPPH method and calculated IC50 values. All trans-amides were characterized by 1H-NMR, 13C-NMR, 19F-NMR, GC-MS and FTIR spectroscopic techniques.
topic amides
dpph method
antioxidant activity
url https://dergipark.org.tr/en/pub/jotcsa/issue/49279/627805
work_keys_str_mv AT ozguryilmaz synthesisoftransdiamidederivativesfromfumarylchlorideanddeterminationofdpphscavengingactivityofsynthesizedmolecules
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