Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules
In this work, new trans-diamide derivatives were synthesized with the reaction between fumaryl chloride and substituted anilines. After the successful synthesis of trans-amides, the antioxidant activity of all synthesized molecules was investigated via the DPPH method and calculated IC50 values. Al...
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| Format: | Article |
| Language: | English |
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Turkish Chemical Society
2020-02-01
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| Series: | Journal of the Turkish Chemical Society, Section A: Chemistry |
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| Online Access: | https://dergipark.org.tr/en/pub/jotcsa/issue/49279/627805 |
| Summary: | In this work, new trans-diamide derivatives were synthesized with the reaction between fumaryl chloride and substituted anilines. After the successful synthesis of trans-amides, the antioxidant activity of all synthesized molecules was investigated via the DPPH method and calculated IC50 values. All trans-amides were characterized by 1H-NMR, 13C-NMR, 19F-NMR, GC-MS and FTIR spectroscopic techniques. |
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| ISSN: | 2149-0120 |