Inhibiting N-acyl-homoserine lactone synthesis and quenching Pseudomonas quinolone quorum sensing to attenuate virulence

Inhibiting N-acyl-homoserine lactone synthesis and quenching Pseudomonas quinolone quorum sensing to attenuate virulence

Bacteria sense their own population size, tune the expression of responding genes and behave accordingly to environmental stimuli by secreting signalling molecules. This phenomenon is termed as quorum sensing (QS). By exogenously manipulating the signal transduction bacterial population behaviours c...

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Bibliographic Details
Main Authors:	Kok Gan eChan, Yi-Chia eLiu, Chien-Yi eChang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-10-01
Series:	Frontiers in Microbiology
Subjects:	Pseudomonas aeruginosa PQS quorum sensing (QS) quorum quenching N-Acyl-homoserine lactone alkylquinolone
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01173/full

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