Farnesoid X receptor regulates forkhead Box O3a activation in ethanol-induced autophagy and hepatotoxicity

Farnesoid X receptor regulates forkhead Box O3a activation in ethanol-induced autophagy and hepatotoxicity

Alcoholic liver disease encompasses a wide spectrum of pathogenesis including steatosis, fibrosis, cirrhosis, and alcoholic steatohepatitis. Autophagy is a lysosomal degradation process that degrades cellular proteins and damaged/excess organelles, and serves as a protective mechanism in response t...

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Bibliographic Details
Main Authors: Sharon Manley, Hong-Min Ni, Jessica A. Williams, Bo Kong, Luciano DiTacchio, Grace Guo, Wen-Xing Ding
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Redox Biology
Subjects:
Autophagy
Farnesoid X receptor
FoxO3a
Alcohol
Liver injury
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231714000974

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