Topoisomerase I but not thymidylate synthase is associated with improved outcome in patients with resected colorectal cancer treated with irinotecan containing adjuvant chemotherapy
<p>Abstract</p> <p>Background</p> <p>Thymidylate synthase (TS) and Topoisomerase I (Topo I) are significant biomarkers in colorectal cancer (CRC). We aimed to study the expression of TS and Topo I in patients with resected CRC who received adjuvant chemotherapy and corr...
Main Authors: | Papakostas Pavlos, Kafiri Georgia, Pentheroudakis George, Xiros Nikolaos, Bobos Mattheos, Karina Maria, Karavasilis Vasilios, Kostopoulos Ioannis, Vrettou Eleni, Fountzilas George |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-09-01
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Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/9/339 |
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