The BtaF Adhesin Is Necessary for Full Virulence During Respiratory Infection by Brucella suis and Is a Novel Immunogen for Nasal Vaccination Against Brucella Infection

The BtaF Adhesin Is Necessary for Full Virulence During Respiratory Infection by Brucella suis and Is a Novel Immunogen for Nasal Vaccination Against Brucella Infection

Brucella enters their hosts mostly through mucosae from where it spreads systemically. Adhesion to extracellular matrix (ECM) components or to host cells is important for the infectious process, and is mediated by several adhesins, including the BtaF trimeric autotransporter. Although Th1 responses...

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Bibliographic Details
Main Authors: Florencia Muñoz González, Gabriela Sycz, Iván M. Alonso Paiva, Dirk Linke, Angeles Zorreguieta, Pablo C. Baldi, Mariana C. Ferrero
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
Brucella suis
bacterial adhesins
BtaF autotransporter
respiratory infection
nasal immunization
mucosal immunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01775/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01775/full

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