Using Sensitivity Analysis to Develop a Validated Computational Model of Post-operative Calvarial Growth in Sagittal Craniosynostosis

Using Sensitivity Analysis to Develop a Validated Computational Model of Post-operative Calvarial Growth in Sagittal Craniosynostosis

Craniosynostosis is the premature fusion of one or more sutures across the calvaria, resulting in morphological and health complications that require invasive corrective surgery. Finite element (FE) method is a powerful tool that can aid with preoperative planning and post-operative predictions of c...

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Bibliographic Details
Main Authors: Connor Cross, Roman H. Khonsari, Leila Galiay, Giovanna Patermoster, David Johnson, Yiannis Ventikos, Mehran Moazen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
craniosynostosis
cerebrospinal fluid
finite element
calvarial growth
sagittal synostosis
biomechanics
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.621249/full

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