Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties

Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties

Polymer supported dichlorophosphate (PEG-OPOCl2) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized compo...

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Main Authors: Ola Lasekan, Palanisamy Arulselvan, Syed Rasheed, Sharida Fakurazi, Shaik Ibrahim Khalivulla, Kalla Reddi Mohan Naidu, Faridah Abas
Format: Article
Language:English
Published: MDPI AG 2013-01-01
Series:International Journal of Molecular Sciences
Subjects:
cytotoxicity properties
bisindolylmethanes
dibisindolylmethanes
green catalyst
Online Access:http://www.mdpi.com/1422-0067/14/1/1843
id doaj-e5a52718d47f4fe484cf8ec174b34a54
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spelling doaj-e5a52718d47f4fe484cf8ec174b34a542020-11-24T21:51:58ZengMDPI AGInternational Journal of Molecular Sciences1422-00672013-01-011411843185310.3390/ijms14011843Synthesis of Bisindolylmethanes and Their Cytotoxicity PropertiesOla LasekanPalanisamy ArulselvanSyed RasheedSharida FakuraziShaik Ibrahim KhalivullaKalla Reddi Mohan NaiduFaridah AbasPolymer supported dichlorophosphate (PEG-OPOCl2) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized compounds and their anti-cancer activity are evaluated.http://www.mdpi.com/1422-0067/14/1/1843cytotoxicity propertiesbisindolylmethanesdibisindolylmethanesgreen catalyst
collection DOAJ
language English
format Article
sources DOAJ
author Ola Lasekan
Palanisamy Arulselvan
Syed Rasheed
Sharida Fakurazi
Shaik Ibrahim Khalivulla
Kalla Reddi Mohan Naidu
Faridah Abas
spellingShingle Ola Lasekan
Palanisamy Arulselvan
Syed Rasheed
Sharida Fakurazi
Shaik Ibrahim Khalivulla
Kalla Reddi Mohan Naidu
Faridah Abas
Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties
International Journal of Molecular Sciences
cytotoxicity properties
bisindolylmethanes
dibisindolylmethanes
green catalyst
author_facet Ola Lasekan
Palanisamy Arulselvan
Syed Rasheed
Sharida Fakurazi
Shaik Ibrahim Khalivulla
Kalla Reddi Mohan Naidu
Faridah Abas
author_sort Ola Lasekan
title Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties
title_short Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties
title_full Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties
title_fullStr Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties
title_full_unstemmed Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties
title_sort synthesis of bisindolylmethanes and their cytotoxicity properties
publisher MDPI AG
series International Journal of Molecular Sciences
issn 1422-0067
publishDate 2013-01-01
description Polymer supported dichlorophosphate (PEG-OPOCl2) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized compounds and their anti-cancer activity are evaluated.
topic cytotoxicity properties
bisindolylmethanes
dibisindolylmethanes
green catalyst
url http://www.mdpi.com/1422-0067/14/1/1843
work_keys_str_mv AT olalasekan synthesisofbisindolylmethanesandtheircytotoxicityproperties
AT palanisamyarulselvan synthesisofbisindolylmethanesandtheircytotoxicityproperties
AT syedrasheed synthesisofbisindolylmethanesandtheircytotoxicityproperties
AT sharidafakurazi synthesisofbisindolylmethanesandtheircytotoxicityproperties
AT shaikibrahimkhalivulla synthesisofbisindolylmethanesandtheircytotoxicityproperties
AT kallareddimohannaidu synthesisofbisindolylmethanesandtheircytotoxicityproperties
AT faridahabas synthesisofbisindolylmethanesandtheircytotoxicityproperties
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