Diffusion weighted imaging evaluated the early therapy effect of tamoxifen in an MNU-induced mammary cancer rat model.

To assess the optimal time point of diffusion-weighted imaging (DWI) for early prognosis of breast cancer following tamoxifen therapy using a methylnitrosourea (MNU)-induced ER-positive breast-cancer model.Two groups of Sprague-Dawley rats (n = 15 for group 1; n = 10 for group 2) were used. All anim...

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Bibliographic Details
Main Authors: Guihua Zhai, Clinton J Grubbs, Cecil R Stockard, Heidi R Umphrey, T Mark Beasley, Hyunki Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3660312?pdf=render