Direct injection HILICâMS/MS analysis of darunavir in rat plasma applying supported liquid extraction
A novel bioanalytical method was developed and validated for the quantitative determination of darunavir (DRV) in rat plasma by employing hydrophilic interaction chromatography and tandem mass spectrometry (HILICâMS/MS) with supported liquid extraction (SLE). Irbesartan (IRB) was used as an internal...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2015-02-01
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| Series: | Journal of Pharmaceutical Analysis |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2095177914000422 |