Molecular dynamics simulations of the mammalian glutamate transporter EAAT3.

Excitatory amino acid transporters (EAATs) are membrane proteins that enable sodium-coupled uptake of glutamate and other amino acids into neurons. Crystal structures of the archaeal homolog GltPh have been recently determined both in the inward- and outward-facing conformations. Here we construct h...

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Bibliographic Details
Main Authors: Germano Heinzelmann, Serdar Kuyucak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3958442?pdf=render