A bioinspired and biocompatible ortho-sulfiliminyl phenol synthesis

Functionalization of C-H bonds typically requires harsh reagents or metal catalysts. Here the authors report a metal-free C-H sulfenylation/rearrangement to form C-S and S=N bonds under simple, biocompatible conditions, and apply this to the synthesis of fluorogenic phospholipid vesicles.

Bibliographic Details
Main Authors:	Feng Xiong, Liang Lu, Tian-Yu Sun, Qian Wu, Dingyuan Yan, Ying Chen, Xinhao Zhang, Wei Wei, Yi Lu, Wei-Yin Sun, Jie Jack Li, Jing Zhao
Format:	Article
Language:	English
Published:	Nature Publishing Group 2017-06-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/ncomms15912

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spelling	doaj-e57c5fc7d52645ee838742b35e4dd45c2021-05-11T07:20:12ZengNature Publishing GroupNature Communications2041-17232017-06-01811710.1038/ncomms15912A bioinspired and biocompatible ortho-sulfiliminyl phenol synthesisFeng Xiong0Liang Lu1Tian-Yu Sun2Qian Wu3Dingyuan Yan4Ying Chen5Xinhao Zhang6Wei Wei7Yi Lu8Wei-Yin Sun9Jie Jack Li10Jing Zhao11State Key Laboratory of Coordination Chemistry, Institute of Chemistry and BioMedical Sciences, School of Chemistry and Chemical Engineering, Nanjing UniversityState Key Laboratory of Coordination Chemistry, Institute of Chemistry and BioMedical Sciences, School of Chemistry and Chemical Engineering, Nanjing UniversityGuangdong Key Laboratory of Nano-Micro Material Research, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate SchoolGuangdong Key Laboratory of Nano-Micro Material Research, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate SchoolState Key Laboratory of Coordination Chemistry, Institute of Chemistry and BioMedical Sciences, School of Chemistry and Chemical Engineering, Nanjing UniversityGuangdong Key Laboratory of Nano-Micro Material Research, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate SchoolGuangdong Key Laboratory of Nano-Micro Material Research, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate SchoolState Key Laboratory of Coordination Chemistry, Institute of Chemistry and BioMedical Sciences, School of Chemistry and Chemical Engineering, Nanjing UniversityState Key Laboratory of Coordination Chemistry, Institute of Chemistry and BioMedical Sciences, School of Chemistry and Chemical Engineering, Nanjing UniversityState Key Laboratory of Coordination Chemistry, Institute of Chemistry and BioMedical Sciences, School of Chemistry and Chemical Engineering, Nanjing UniversityDepartment of Chemistry, University of San FranciscoState Key Laboratory of Coordination Chemistry, Institute of Chemistry and BioMedical Sciences, School of Chemistry and Chemical Engineering, Nanjing UniversityFunctionalization of C-H bonds typically requires harsh reagents or metal catalysts. Here the authors report a metal-free C-H sulfenylation/rearrangement to form C-S and S=N bonds under simple, biocompatible conditions, and apply this to the synthesis of fluorogenic phospholipid vesicles.https://doi.org/10.1038/ncomms15912
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Feng Xiong Liang Lu Tian-Yu Sun Qian Wu Dingyuan Yan Ying Chen Xinhao Zhang Wei Wei Yi Lu Wei-Yin Sun Jie Jack Li Jing Zhao
spellingShingle	Feng Xiong Liang Lu Tian-Yu Sun Qian Wu Dingyuan Yan Ying Chen Xinhao Zhang Wei Wei Yi Lu Wei-Yin Sun Jie Jack Li Jing Zhao A bioinspired and biocompatible ortho-sulfiliminyl phenol synthesis Nature Communications
author_facet	Feng Xiong Liang Lu Tian-Yu Sun Qian Wu Dingyuan Yan Ying Chen Xinhao Zhang Wei Wei Yi Lu Wei-Yin Sun Jie Jack Li Jing Zhao
author_sort	Feng Xiong
title	A bioinspired and biocompatible ortho-sulfiliminyl phenol synthesis
title_short	A bioinspired and biocompatible ortho-sulfiliminyl phenol synthesis
title_full	A bioinspired and biocompatible ortho-sulfiliminyl phenol synthesis
title_fullStr	A bioinspired and biocompatible ortho-sulfiliminyl phenol synthesis
title_full_unstemmed	A bioinspired and biocompatible ortho-sulfiliminyl phenol synthesis
title_sort	bioinspired and biocompatible ortho-sulfiliminyl phenol synthesis
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2017-06-01
description	Functionalization of C-H bonds typically requires harsh reagents or metal catalysts. Here the authors report a metal-free C-H sulfenylation/rearrangement to form C-S and S=N bonds under simple, biocompatible conditions, and apply this to the synthesis of fluorogenic phospholipid vesicles.
url	https://doi.org/10.1038/ncomms15912
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A bioinspired and biocompatible ortho-sulfiliminyl phenol synthesis

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