A bioinspired and biocompatible ortho-sulfiliminyl phenol synthesis

Functionalization of C-H bonds typically requires harsh reagents or metal catalysts. Here the authors report a metal-free C-H sulfenylation/rearrangement to form C-S and S=N bonds under simple, biocompatible conditions, and apply this to the synthesis of fluorogenic phospholipid vesicles.

Bibliographic Details
Main Authors: Feng Xiong, Liang Lu, Tian-Yu Sun, Qian Wu, Dingyuan Yan, Ying Chen, Xinhao Zhang, Wei Wei, Yi Lu, Wei-Yin Sun, Jie Jack Li, Jing Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15912
Description
Summary:Functionalization of C-H bonds typically requires harsh reagents or metal catalysts. Here the authors report a metal-free C-H sulfenylation/rearrangement to form C-S and S=N bonds under simple, biocompatible conditions, and apply this to the synthesis of fluorogenic phospholipid vesicles.
ISSN:2041-1723