In Vitro and In Vivo Studies of Non-Platinum-Based Halogenated Compounds as Potent Antitumor Agents for Natural Targeted Chemotherapy of Cancers

In Vitro and In Vivo Studies of Non-Platinum-Based Halogenated Compounds as Potent Antitumor Agents for Natural Targeted Chemotherapy of Cancers

Based on a molecular-mechanism-based anticancer drug discovery program enabled by an innovative femtomedicine approach, we have found a previously unknown class of non-platinum-based halogenated molecules (called FMD compounds) as potent antitumor agents for effective treatment of cancers. Here, we...

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Bibliographic Details
Main Authors: Qing-Bin Lu, Qin-Rong Zhang, Ning Ou, Chun-Rong Wang, Jenny Warrington
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:EBioMedicine
Subjects:
Femtomedicine
Targeted chemotherapy
Antitumor agents
Non-platinum-based compounds
Reductive DNA damage
Online Access:http://www.sciencedirect.com/science/article/pii/S235239641500105X

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