Induced Pluripotent Stem Cells: Advances in the Quest for Genetic Stability during Reprogramming Process

Induced Pluripotent Stem Cells: Advances in the Quest for Genetic Stability during Reprogramming Process

Evaluation of the extent and nature of induced pluripotent stem cell (iPSC) genetic instability is important for both basic research and future clinical use. As previously demonstrated regarding embryonic stem cells, such DNA aberrations might affect the differentiation capacity of the cells and inc...

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Bibliographic Details
Main Authors: Valentina Turinetto, Luca Orlando, Claudia Giachino
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:International Journal of Molecular Sciences
Subjects:
DNA damage response
genetic stability
genetic variation
induced pluripotent stem cell
reprogramming
Online Access:https://www.mdpi.com/1422-0067/18/9/1952

Internet

https://www.mdpi.com/1422-0067/18/9/1952

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