RNA Aptamers as Molecular Tools to Study the Functionality of the Hepatitis C Virus CRE Region

RNA Aptamers as Molecular Tools to Study the Functionality of the Hepatitis C Virus CRE Region

Background: Hepatitis C virus (HCV) contains a (+) ssRNA genome with highly conserved structural, functional RNA domains, many of them with unknown roles for the consecution of the viral cycle. Such genomic domains are candidate therapeutic targets. This study reports the functional characterization...

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Bibliographic Details
Main Authors: Alba Fernández-Sanlés, Beatriz Berzal-Herranz, Rodrigo González-Matamala, Pablo Ríos-Marco, Cristina Romero-López, Alfredo Berzal-Herranz
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:Molecules
Subjects:
RNA aptamers
antiHCV Aptamers
HCV genome
CRE
5BSL3.2
functional RNA domain
Online Access:http://www.mdpi.com/1420-3049/20/9/16030

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