Anti-Cancer and Immunomodulatory Activity of a Polyethylene Glycol-Betulinic Acid Conjugate on Pancreatic Cancer Cells

Anti-Cancer and Immunomodulatory Activity of a Polyethylene Glycol-Betulinic Acid Conjugate on Pancreatic Cancer Cells

Drug delivery systems involving polymer therapeutics enhance drug potency by improved solubility and specificity and may assist in circumventing chemoresistance in pancreatic cancer (PC). We compared the effectiveness of the naturally occurring drug, betulinic acid (BA), alone and in a polymer conju...

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Bibliographic Details
Main Authors: Pascaline Nanga Fru, Ekene Emmanuel Nweke, Nompumelelo Mthimkhulu, Sindisiwe Mvango, Marietha Nel, Lynne Alison Pilcher, Mohammed Balogun
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Life
Subjects:
betulinic acid
polyethylene glycol
apoptosis
pancreatic cancer
polymer therapeutics
Online Access:https://www.mdpi.com/2075-1729/11/6/462

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https://www.mdpi.com/2075-1729/11/6/462

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