Blood-Brain Barrier Disruption Increases Amyloid-Related Pathology in TgSwDI Mice

Blood-Brain Barrier Disruption Increases Amyloid-Related Pathology in TgSwDI Mice

In Alzheimer’s disease (AD), several studies have reported blood-brain barrier (BBB) breakdown with compromised function. P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) are transport proteins localized at the BBB luminal membrane and play an important role in the clearance of amyl...

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Bibliographic Details
Main Authors:	Ihab M. Abdallah, Kamal M. Al-Shami, Euitaek Yang, Amal Kaddoumi
Format:	Article
Language:	English
Published:	MDPI AG 2021-01-01
Series:	International Journal of Molecular Sciences
Subjects:	Alzheimer’s disease CAA blood-brain barrier amyloid-β P-glycoprotein breast cancer resistance protein
Online Access:	https://www.mdpi.com/1422-0067/22/3/1231

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