Cytotoxic Activity against A549 Human Lung Cancer Cells and ADMET Analysis of New Pyrazole Derivatives

Cytotoxic Activity against A549 Human Lung Cancer Cells and ADMET Analysis of New Pyrazole Derivatives

Two new pyrazole derivatives, namely compound <b>1</b> and compound <b>2,</b> have been synthesized, and their biological activity has been evaluated. Monocrystals of the obtained compounds were thoroughly investigated using single-crystal X-ray diffraction analysis, FTIR spe...

Full description

Bibliographic Details
Main Authors: Agnieszka Czylkowska, Małgorzata Szczesio, Anita Raducka, Bartłomiej Rogalewicz, Paweł Kręcisz, Kamila Czarnecka, Paweł Szymański, Monika Pitucha, Tomasz Pawlak
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
cytotoxic activity
pyrazole derivatives
MTT assay
ADMET analysis
single-crystal diffraction
FTIR spectroscopy
Online Access:https://www.mdpi.com/1422-0067/22/13/6692

Internet

https://www.mdpi.com/1422-0067/22/13/6692

Similar Items