Endogenous Wnt/beta-catenin signaling is required for cardiac differentiation in human embryonic stem cells.

Endogenous Wnt/beta-catenin signaling is required for cardiac differentiation in human embryonic stem cells.

Wnt/beta-catenin signaling is an important regulator of differentiation and morphogenesis that can also control stem cell fates. Our group has developed an efficient protocol to generate cardiomyocytes from human embryonic stem (ES) cells via induction with activin A and BMP4.We tested the hypothesi...

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Bibliographic Details
Main Authors:	Sharon L Paige, Tomoaki Osugi, Olga K Afanasiev, Lil Pabon, Hans Reinecke, Charles E Murry
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-06-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC2886114?pdf=render

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