Role of EphA2 in host defense against oro-pharyngeal candidiasis
Oral defense should be able to sense the burden of, and distinguish between fungal commensals and pathogens, so that an adequate inflammatory response can be set up. Recently, Ephrin type-A receptor 2 (EphA2) was identified on oral epithelial cells and neutrophils that recognizes Candida albicans an...
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Series: | Journal of Oral Microbiology |
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Online Access: | http://dx.doi.org/10.1080/20002297.2020.1711619 |
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doaj-e5259c336d444291a4a1728110b2b5d02021-06-02T08:43:38ZengTaylor & Francis GroupJournal of Oral Microbiology2000-22972020-01-0112110.1080/20002297.2020.17116191711619Role of EphA2 in host defense against oro-pharyngeal candidiasisIngar Olsen0University of OsloOral defense should be able to sense the burden of, and distinguish between fungal commensals and pathogens, so that an adequate inflammatory response can be set up. Recently, Ephrin type-A receptor 2 (EphA2) was identified on oral epithelial cells and neutrophils that recognizes Candida albicans and induces adaptive protective host responses against this organism. The studies have increased our knowledge of how epithelial cells and neutrophils contribute to host defense against oral yeast infection.http://dx.doi.org/10.1080/20002297.2020.1711619oral epithelial cellsneutrophilsoral candidiasiscommensalspathogens |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ingar Olsen |
spellingShingle |
Ingar Olsen Role of EphA2 in host defense against oro-pharyngeal candidiasis Journal of Oral Microbiology oral epithelial cells neutrophils oral candidiasis commensals pathogens |
author_facet |
Ingar Olsen |
author_sort |
Ingar Olsen |
title |
Role of EphA2 in host defense against oro-pharyngeal candidiasis |
title_short |
Role of EphA2 in host defense against oro-pharyngeal candidiasis |
title_full |
Role of EphA2 in host defense against oro-pharyngeal candidiasis |
title_fullStr |
Role of EphA2 in host defense against oro-pharyngeal candidiasis |
title_full_unstemmed |
Role of EphA2 in host defense against oro-pharyngeal candidiasis |
title_sort |
role of epha2 in host defense against oro-pharyngeal candidiasis |
publisher |
Taylor & Francis Group |
series |
Journal of Oral Microbiology |
issn |
2000-2297 |
publishDate |
2020-01-01 |
description |
Oral defense should be able to sense the burden of, and distinguish between fungal commensals and pathogens, so that an adequate inflammatory response can be set up. Recently, Ephrin type-A receptor 2 (EphA2) was identified on oral epithelial cells and neutrophils that recognizes Candida albicans and induces adaptive protective host responses against this organism. The studies have increased our knowledge of how epithelial cells and neutrophils contribute to host defense against oral yeast infection. |
topic |
oral epithelial cells neutrophils oral candidiasis commensals pathogens |
url |
http://dx.doi.org/10.1080/20002297.2020.1711619 |
work_keys_str_mv |
AT ingarolsen roleofepha2inhostdefenseagainstoropharyngealcandidiasis |
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1721406404230643712 |