Role of EphA2 in host defense against oro-pharyngeal candidiasis

Oral defense should be able to sense the burden of, and distinguish between fungal commensals and pathogens, so that an adequate inflammatory response can be set up. Recently, Ephrin type-A receptor 2 (EphA2) was identified on oral epithelial cells and neutrophils that recognizes Candida albicans an...

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Main Author: Ingar Olsen
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Journal of Oral Microbiology
Subjects:
Online Access:http://dx.doi.org/10.1080/20002297.2020.1711619
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spelling doaj-e5259c336d444291a4a1728110b2b5d02021-06-02T08:43:38ZengTaylor & Francis GroupJournal of Oral Microbiology2000-22972020-01-0112110.1080/20002297.2020.17116191711619Role of EphA2 in host defense against oro-pharyngeal candidiasisIngar Olsen0University of OsloOral defense should be able to sense the burden of, and distinguish between fungal commensals and pathogens, so that an adequate inflammatory response can be set up. Recently, Ephrin type-A receptor 2 (EphA2) was identified on oral epithelial cells and neutrophils that recognizes Candida albicans and induces adaptive protective host responses against this organism. The studies have increased our knowledge of how epithelial cells and neutrophils contribute to host defense against oral yeast infection.http://dx.doi.org/10.1080/20002297.2020.1711619oral epithelial cellsneutrophilsoral candidiasiscommensalspathogens
collection DOAJ
language English
format Article
sources DOAJ
author Ingar Olsen
spellingShingle Ingar Olsen
Role of EphA2 in host defense against oro-pharyngeal candidiasis
Journal of Oral Microbiology
oral epithelial cells
neutrophils
oral candidiasis
commensals
pathogens
author_facet Ingar Olsen
author_sort Ingar Olsen
title Role of EphA2 in host defense against oro-pharyngeal candidiasis
title_short Role of EphA2 in host defense against oro-pharyngeal candidiasis
title_full Role of EphA2 in host defense against oro-pharyngeal candidiasis
title_fullStr Role of EphA2 in host defense against oro-pharyngeal candidiasis
title_full_unstemmed Role of EphA2 in host defense against oro-pharyngeal candidiasis
title_sort role of epha2 in host defense against oro-pharyngeal candidiasis
publisher Taylor & Francis Group
series Journal of Oral Microbiology
issn 2000-2297
publishDate 2020-01-01
description Oral defense should be able to sense the burden of, and distinguish between fungal commensals and pathogens, so that an adequate inflammatory response can be set up. Recently, Ephrin type-A receptor 2 (EphA2) was identified on oral epithelial cells and neutrophils that recognizes Candida albicans and induces adaptive protective host responses against this organism. The studies have increased our knowledge of how epithelial cells and neutrophils contribute to host defense against oral yeast infection.
topic oral epithelial cells
neutrophils
oral candidiasis
commensals
pathogens
url http://dx.doi.org/10.1080/20002297.2020.1711619
work_keys_str_mv AT ingarolsen roleofepha2inhostdefenseagainstoropharyngealcandidiasis
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