Effect of Caloric Restriction on Hepatic Sinusoidal System and Stellate Cells in Mice

Aging associated changes in liver include reduced hepatic blood flow, increased number of stellate cells, and collagen deposits in perisinusoidal space. We tested the possibility of mitigating these changes with caloric restriction. Two-month-old mice were subjected to 30 percent caloric restriction...

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Bibliographic Details
Main Authors: Jian Chen, Kara King, Jian X. Zhang
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Journal of Aging Research
Online Access:http://dx.doi.org/10.1155/2014/670890