Disulfiram/copper complex inhibits proliferation and induces apoptosis in hepatocellular carcinoma cells through dephosphorylation and mitochondrial translocation of Drp1

Objective To determine the effects of disulfiram/copper complex, copper(Ⅱ) diethyldithiocarbamate (CuET) on the proliferation and apoptosis of hepatocellular carcinoma cells, and investigate the molecular mechanisms. Methods MTT assay was used to detect cell viability in the hepatocellular carcinoma...

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Bibliographic Details
Main Authors: LI Jie, HU Jinjiao, JIANG Xiuxing, GAO Ning
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2020-12-01
Series:Di-san junyi daxue xuebao
Subjects:
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202007186.htm